PP-2T (C₂₂₅H₃₄₈N₄₈O₆₈, 39aa synthetic research peptide, MW ~4,813 Da, CAS 2023788-19-2). Research-grade peptide on a GIP backbone with Aib²·¹³ and a C20 fatty diacid, used in dual-receptor cAMP-signaling assays, receptor-binding characterization at GIPR and GLP-1R, and BCAA catabolism research. ≥99% purity, lyophilized. Research use only. Not for human consumption.
PP-2T (Tirzepatide)
Research-grade peptide on a GIP backbone with Aib²·¹³ and a C20 fatty diacid, used…
Price range: $47.85 through $149.00
| Title | Range | Discount |
|---|---|---|
| Bulk Discount | 3 - 5 | 5% |
| Bulk Discount | 6 - 10 | 10% |
| >11 Bulk Discount | 11 + | 15% |
Buy more, save more: 5% off at 3+ · 10% off at 6+ · 15% off at 11+. Applied automatically at checkout.
- Lab-grade COA
- 99%+ purity
- 24-hour shipping
- Refund-backed
For research use only. Not for human consumption. All products are sold strictly as reference standards for in-vitro laboratory research and are not intended to diagnose, treat, cure, or prevent any disease.
Description
PP-2T is a synthetic 39-amino acid research peptide (CAS 2023788-19-2, molecular formula C₂₂₅H₃₄₈N₄₈O₆₈, MW ~4,813.45 Da) constructed on a native GIP (glucose-dependent insulinotropic polypeptide) backbone. The peptide features two non-natural α-aminoisobutyric acid (Aib) residues at positions 2 and 13 for dipeptidyl peptidase-IV (DPP-IV) resistance, and a C20 fatty diacid (eicosanedioic acid) conjugated to Lys20 via a glutamic acid and dual AEEA (aminoethoxyethoxyacetic acid) linker enabling in vitro albumin-binding behavior. In cellular assays, PP-2T exhibits imbalanced binding affinity favoring GIPR over GLP-1R and demonstrates biased signaling toward cAMP generation over β-arrestin recruitment at GLP-1R.
In laboratory research, PP-2T is utilized in dual-receptor cAMP accumulation assays, biased-signaling characterization at GLP-1R, GIPR-mediated cAMP pathway activation studies, branched-chain amino acid (BCAA) catabolism investigations in brown adipose tissue cell models, comparative in-vitro structure–activity studies versus single-receptor (GLP-1R-only) research peptides, and Akt/mTOR signaling pathway research.
Supplied as a lyophilized powder with ≥99% purity verified by HPLC. For storage and handling conditions, refer to the Certificate of Analysis provided with each lot. This product is intended strictly for laboratory research use only (RUO) and is not for human consumption, therapeutic use, or any diagnostic purposes.
Third-Party Lab Analysis
Every batch is independently tested by a USA-based, ISO/IEC 17025-accredited third-party laboratory. Download or preview the Certificate of Analysis for each lot below.
10mg
20mg
30mg
50mg
Additional information
| Vial Size | 10mg, 20mg, 30mg, 50mg |
|---|
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