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PT-141 (Bremelanotide, C₅₀H₆₈N₁₄O₁₀, cyclic 7aa, MW ~1,025 Da, CAS 189691-06-3). Synthetic cyclic peptide that binds at MC3R/MC4R for in-vitro melanocortin signaling, biased-signaling characterization, and neuropeptide pathway research. ≥99% purity, lyophilized. Research use only. Not for human consumption.

Specifications
Formula C₅₀H₆₈N₁₄O₁₀
CAS 189691-06-3
Melanocortin Receptor (MCR) Ligand RUO

PT-141

For Research Use Only — Not for Human Consumption

Synthetic cyclic peptide that binds at MC3R/MC4R for in-vitro melanocortin signaling, biased-signaling characterization, and…

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Certificate of Analysis preview
Certificate of Analysis
Lot 04/24/2026 · purity confirmed by HPLC
View COA (PDF)
  • Lab-grade COA
  • 99%+ purity
  • 24-hour shipping
  • Refund-backed
RUO

For research use only. Not for human consumption. All products are sold strictly as reference standards for in-vitro laboratory research and are not intended to diagnose, treat, cure, or prevent any disease.

Description

PT-141 (Bremelanotide) is a synthetic cyclic heptapeptide with the sequence Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-OH, molecular formula C₅₀H₆₈N₁₄O₁₀, a molecular weight of approximately 1,025.18 Da, and CAS number 189691-06-3. PT-141 is a C-terminal hydrolysis derivative of Melanotan-2 and binds at MC3R and MC4R subtypes of the melanocortin receptor family in research models.

In laboratory research, PT-141 is utilized in melanocortin receptor-mediated CNS signaling studies, hypothalamic neuropeptide pathway investigations, dopaminergic and oxytocinergic system interaction experiments, MC4R-dependent behavioral neuroscience models, cAMP production assays, β-arrestin recruitment studies (BRET/FRET-based), and functional-selectivity (biased-signaling) characterization at melanocortin receptor subtypes.

Supplied as a lyophilized powder with ≥99% purity verified by HPLC. For storage and handling conditions, refer to the Certificate of Analysis provided with each lot. This product is intended strictly for laboratory research use only (RUO) and is not for human consumption, therapeutic use, or any diagnostic purposes.

Third-Party Lab Analysis

Every batch is independently tested by a USA-based, ISO/IEC 17025-accredited third-party laboratory. Download or preview the Certificate of Analysis for each lot below.

10mg

Lot: PP412-26-001Tested: 04/24/2026
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Additional information

Vial Size

10mg, 5mg

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