NAD+ (Nicotinamide Adenine Dinucleotide, C₂₁H₂₇N₇O₁₄P₂, MW 663.43 Da, CAS 53-84-9). Redox coenzyme and consumed substrate for sirtuin, PARP, and CD38 enzymatic pathway research. ≥99% purity, lyophilized. Research use only. Not for human consumption.
NAD+
Redox coenzyme and consumed substrate for sirtuin, PARP, and CD38 enzymatic pathway research.
$51.99
$44.19
| Title | Range | Discount |
|---|---|---|
| Bulk Discount | 3 - 5 | 5% |
| Bulk Discount | 6 - 10 | 10% |
| >11 Bulk Discount | 11 + | 15% |
Buy more, save more: 5% off at 3+ · 10% off at 6+ · 15% off at 11+. Applied automatically at checkout.
- Lab-grade COA
- 99%+ purity
- 24-hour shipping
- Refund-backed
For research use only. Not for human consumption. All products are sold strictly as reference standards for in-vitro laboratory research and are not intended to diagnose, treat, cure, or prevent any disease.
Description
NAD+ (Nicotinamide Adenine Dinucleotide) is the oxidized form of a vital dinucleotide coenzyme present in all living cells, with the molecular formula C₂₁H₂₇N₇O₁₄P₂, a molecular weight of approximately 663.43 Da, and CAS number 53-84-9. As a central mediator in cellular redox biochemistry, NAD+ participates in over 500 known enzymatic reactions, functioning as a primary electron carrier in glycolysis, the tricarboxylic acid (TCA) cycle, and the mitochondrial electron transport chain. Beyond its role as a coenzyme, NAD+ serves as a consumed substrate for three major enzyme families: sirtuins (SIRT1–SIRT7, class III histone deacetylases), poly(ADP-ribose) polymerases (PARPs, involved in DNA damage repair signaling), and cyclic ADP-ribose synthases (CD38/CD157 ectoenzymes).
In laboratory research, NAD+ is utilized in sirtuin deacetylase activity assays, PARP enzymatic activity measurements, CD38 ectoenzyme kinetic studies, mitochondrial electron transport chain functional assays, and cellular metabolic flux analysis using isotope tracing. Researchers also employ NAD+ in studies of NAD+-dependent calcium signaling via cADPR production, epigenetic regulation through histone deacetylation, and age-related changes in the NAD+ metabolome.
Supplied as a lyophilized powder with ≥99% purity verified by HPLC. For storage and handling conditions, refer to the Certificate of Analysis provided with each lot. This product is intended strictly for laboratory research use only (RUO) and is not for human consumption, therapeutic use, or any diagnostic purposes.
Third-Party Lab Analysis
Every batch is independently tested by a USA-based, ISO/IEC 17025-accredited third-party laboratory. Download or preview the Certificate of Analysis for each lot below.
500mg
Additional information
| Vial Size | 500mg, 1000mg |
|---|
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