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Sermorelin (GRF 1-29 NH₂, C₁₄₉H₂₄₆N₄₄O₄₂S, 29aa, MW ~3,358 Da, CAS 86168-78-7). Synthetic peptide for in-vitro pituitary somatotroph receptor binding studies, cAMP/PKA pathway assays, and structure–activity research. ≥99% HPLC purity, lyophilized.

Specifications
Formula C₁₄₉H₂₄₆N₄₄O₄₂S
CAS 86168-78-7
GHS-R / GHRH-R Ligand

Sermorelin

For Research Use Only — Not for Human Consumption

Sale price: Price range: $37.26 through $52.64

Title Range Discount
Bulk Discount 3 - 5 5%
Bulk Discount 6 - 10 10%
>11 Bulk Discount 11 + 15%
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Certificate of Analysis preview
Certificate of Analysis
Lot 08/11/2026 · purity confirmed by HPLC
View COA (PDF)
  • Lab-grade COA
  • 99%+ purity
  • Most orders ship within 24 hours.
  • Refund-backed
  • All Precisely Peptides research peptides are USA-sourced and synthesized in the USA.

Description

Sermorelin (GRF 1-29 NH₂) is a synthetic 29-amino acid peptide corresponding to the N-terminal fragment of human GHRH, molecular formula C₁₄₉H₂₄₆N₄₄O₄₂S, a molecular weight of approximately 3,357.88 Da, and CAS number 86168-78-7. The first 29 residues constitute the minimum sequence required for receptor-binding interactions at GHRH-R in published research models.

In laboratory research, Sermorelin is utilized in pituitary somatotroph receptor-binding assays, cAMP-dependent PKA pathway activation studies, hypothalamic–pituitary in-vitro signaling investigations, competitive-displacement binding assays (¹²⁵I-GHRH tracer), calcium-imaging experiments in pituitary cell lines, and comparative in-vitro structure–activity studies with related synthetic peptides on the GHRH backbone (CJC-1295, tesamorelin).

Supplied as a lyophilized powder with ≥99% purity verified by HPLC. For storage and handling conditions, refer to the Certificate of Analysis provided with each lot. This product is intended strictly for laboratory research use only (RUO) and is not for human consumption, therapeutic use, or any diagnostic purposes.

Third-Party Lab Analysis

Available certificates are independently tested by a USA-based, ISO/IEC 17025-accredited third-party laboratory. Download or preview each documented lot below.

5mg

Lot: PP412-26-001Tested: 04/23/2026
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Lot: PP728-26-001Tested: 08/11/2026
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Additional information

Vial Size

5mg, 10mg

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