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PT-141 (Bremelanotide, C₅₀H₆₈N₁₄O₁₀, cyclic 7aa, MW ~1,025 Da, CAS 189691-06-3). Synthetic cyclic peptide that binds at MC3R/MC4R for in-vitro melanocortin signaling, biased-signaling characterization, and neuropeptide pathway research. ≥99% purity, lyophilized.

Specifications
Formula C₅₀H₆₈N₁₄O₁₀
CAS 189691-06-3
Melanocortin Receptor (MCR) Ligand

PT-141

For Research Use Only — Not for Human Consumption

Sale price: $24.37

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Certificate of Analysis preview
Certificate of Analysis
Lot 04/24/2026 · purity confirmed by HPLC
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  • Lab-grade COA
  • 99%+ purity
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  • Refund-backed
  • All Precisely Peptides research peptides are USA-sourced and synthesized in the USA.

Description

PT-141 (Bremelanotide) is a synthetic cyclic heptapeptide with the sequence Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-OH, molecular formula C₅₀H₆₈N₁₄O₁₀, a molecular weight of approximately 1,025.18 Da, and CAS number 189691-06-3. PT-141 is a C-terminal hydrolysis derivative of Melanotan-2 and binds at MC3R and MC4R subtypes of the melanocortin receptor family in research models.

In laboratory research, PT-141 is utilized in melanocortin receptor-mediated CNS signaling studies, hypothalamic neuropeptide pathway investigations, dopaminergic and oxytocinergic system interaction experiments, MC4R-dependent behavioral neuroscience models, cAMP production assays, β-arrestin recruitment studies (BRET/FRET-based), and functional-selectivity (biased-signaling) characterization at melanocortin receptor subtypes.

Supplied as a lyophilized powder with ≥99% purity verified by HPLC. For storage and handling conditions, refer to the Certificate of Analysis provided with each lot. This product is intended strictly for laboratory research use only (RUO) and is not for human consumption, therapeutic use, or any diagnostic purposes.

Third-Party Lab Analysis

Available certificates are independently tested by a USA-based, ISO/IEC 17025-accredited third-party laboratory. Download or preview each documented lot below.

10mg

Lot: PP412-26-001Tested: 04/24/2026
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Additional information

Vial Size

10mg

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