TB-500 (C₂₁₂H₃₅₀N₅₆O₇₈S, 43aa thymosin β4 fragment, MW ~4,964 Da, CAS 77591-33-4). LKKTETQ actin-binding peptide for cell migration, cytoskeletal dynamics, MMP regulation, and endothelial tube formation research. ≥99% purity, lyophilized.
TB-500
$49.49
- Lab-grade COA
- 99%+ purity
- Most orders ship within 24 hours. Orders placed Saturday or Sunday ship Monday.
- Refund-backed
- All Precisely Peptides research peptides are USA-sourced and synthesized in the USA.Black Label research peptides are produced in cGMP facilities.
Description
TB-500 is a synthetic 43-amino acid peptide (molecular formula C₂₁₂H₃₅₀N₅₆O₇₈S, MW ~4,963.50 Da, CAS 77591-33-4) representing the biologically active region of thymosin beta-4 (Tβ4), the principal G-actin sequestering molecule in eukaryotic cells. The active domain centers on the actin-binding motif LKKTETQ (residues 17-23) responsible for G-actin binding and polymerization regulation.
In laboratory research, TB-500 is utilized in actin cytoskeleton dynamics studies, scratch wound closure assays and transwell migration assays, lamellipodium formation investigations, MMP expression modulation studies, endothelial cell tube formation assays (Matrigel), keratinocyte migration experiments, stem cell differentiation models, Wnt signaling pathway interaction studies, hair follicle stem cell activation research, and cardiac progenitor cell biology investigations.
Supplied as a lyophilized powder with ≥99% purity verified by HPLC. For storage and handling conditions, refer to the Certificate of Analysis provided with each lot. This product is intended strictly for laboratory research use only (RUO) and is not for human consumption, therapeutic use, or any diagnostic purposes.
Additional information
| Vial Size | 10mg |
|---|
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