TB-500 (C₂₁₂H₃₅₀N₅₆O₇₈S, 43aa thymosin β4 fragment, MW ~4,964 Da, CAS 77591-33-4). LKKTETQ actin-binding peptide for cell migration, cytoskeletal dynamics, MMP regulation, and endothelial tube formation research. ≥99% purity, lyophilized. Research use only. Not for human consumption.
TB-500
LKKTETQ actin-binding peptide for cell migration, cytoskeletal dynamics, MMP regulation, and endothelial tube formation…
Price range: $44.64 through $54.14
| Title | Range | Discount |
|---|---|---|
| Bulk Discount | 3 - 5 | 5% |
| Bulk Discount | 6 - 10 | 10% |
| >11 Bulk Discount | 11 + | 15% |
Buy more, save more: 5% off at 3+ · 10% off at 6+ · 15% off at 11+. Applied automatically at checkout.
- Lab-grade COA
- 99%+ purity
- 24-hour shipping
- Refund-backed
For research use only. Not for human consumption. All products are sold strictly as reference standards for in-vitro laboratory research and are not intended to diagnose, treat, cure, or prevent any disease.
Description
TB-500 is a synthetic 43-amino acid peptide (molecular formula C₂₁₂H₃₅₀N₅₆O₇₈S, MW ~4,963.50 Da, CAS 77591-33-4) representing the biologically active region of thymosin beta-4 (Tβ4), the principal G-actin sequestering molecule in eukaryotic cells. The active domain centers on the actin-binding motif LKKTETQ (residues 17-23) responsible for G-actin binding and polymerization regulation.
In laboratory research, TB-500 is utilized in actin cytoskeleton dynamics studies, scratch wound closure assays and transwell migration assays, lamellipodium formation investigations, MMP expression modulation studies, endothelial cell tube formation assays (Matrigel), keratinocyte migration experiments, stem cell differentiation models, Wnt signaling pathway interaction studies, hair follicle stem cell activation research, and cardiac progenitor cell biology investigations.
Supplied as a lyophilized powder with ≥99% purity verified by HPLC. For storage and handling conditions, refer to the Certificate of Analysis provided with each lot. This product is intended strictly for laboratory research use only (RUO) and is not for human consumption, therapeutic use, or any diagnostic purposes.
Third-Party Lab Analysis
Every batch is independently tested by a USA-based, ISO/IEC 17025-accredited third-party laboratory. Download or preview the Certificate of Analysis for each lot below.
Certificates of Analysis will be available shortly. Contact us for immediate requests.
Additional information
| Vial Size | 5mg, 10mg |
|---|
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